How Britain and its allies can tackle the next synthetic opioid menace

Nitazenes are as dangerous as fentanyl and linked to more than 750 deaths in the UK alone since 2023. Further international cooperation with China, their main source, will help – as long as geopolitics doesn’t interfere, says Philip Berry.

The World Today

Published 15 December 2025 — 4 minute READ

Image — A homeless man pictured in San Francisco. To avoid a US-style opioid crisis, the UK must cooperate with China, the main source of nitazenes, says Philip Berry. Photo: Tayfun Coskun/Anadolu via Getty Images.

Philip Berry

Visiting Senior Lecturer, King’s College London

In September, Shabana Mahmood, Britain’s Home Secretary, hosted her counterparts from the Five Eyes intelligence alliance – the United States, Canada, Australia and New Zealand – in London. The annual meeting was convened to discuss the most pressing security challenges facing the Anglosphere countries, and tackling the menace of synthetic opioids was high on the agenda.

Illicit drugs containing fentanyl or other synthetic opioids caused more than 70,000 deaths in the US in 2023 and approximately 50,000 in Canada between 2016 and 2025. The rates of those deaths have dropped recently, but synthetic opioid abuse continues and is present in other countries.

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